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Previous Volume 356:191-194 January 11, 2007 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Oeffinger et al. (Oct. 12 issue)¹ describe the late effects of the treatment of childhood cancer. Pelvic irradiation and alkylating agents increase the risks of infertility, gonadal dysfunction, and premature ovarian failure. The child's sex and age at the time of treatment influence these risks.²

Advances in the freezing of gonadal tissue and oocytes^3,4 can improve the chances that a survivor of childhood cancer will become a parent. Future research by the Childhood Cancer Survivor Study (CCSS) should address the problem of infertility, which is important to survivors of childhood cancer.⁵

Tress Goodwin, M.A.
B. Elizabeth Oosterhuis, . . . [Full Text of this Article]

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