This Journal feature begins with a case vignette that includesa therapeutic recommendation. A discussion of the clinical problemand the mechanism of benefit of this form of therapy follows.Major clinical studies, the clinical use of this therapy, andpotential adverse effects are reviewed. Relevant formal guidelines,if they exist, are presented. The article ends with the author'sclinical recommendations.
A 44-year-old obese woman (height, 1.7 m [65 in.]) has seenher primary care physician for the past 10 years for managementof conditions related to her obesity, including diabetes, hypertension,and gastroesophageal reflux disease. Despite efforts to lose. . . [Full Text of this Article]
The Clinical Problem
Pathophysiology and Effect of Therapy
Clinical Evidence
Clinical Use
Adverse Effects
Areas of Uncertainty
Guidelines
Recommendations
Source Information
From the Duke Weight Loss Surgery Center and the Duke Endosurgery Center, Duke University Medical Center, Durham, NC.
Address reprint requests to Dr. DeMaria at the Duke Endosurgery Center, DUMC-3288, Duke University Medical Center, Durham, NC 27710, or at eric.demaria@duke.edu.
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