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Previous Volume 356:2211-2214 May 24, 2007 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Calverley et al. do not sufficiently emphasize some aspects of their study on the use of salmeterol and fluticasone in patients with chronic obstructive pulmonary disease (COPD) (Feb. 22 issue).¹ Their study, called the Towards a Revolution in COPD Health (TORCH) trial, showed that treatment with fluticasone alone actually increased mortality at the end of 3 years, although the increase was not significant. This finding contrasts markedly with retrospective analyses and meta-analyses showing a substantial reduction in mortality from all causes by about 25% associated with the drug.^2,3 This discrepancy between the results of a well-conducted, randomized, . . . [Full Text of this Article]

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