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Correspondence
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Volume 356:2218-2219 May 24, 2007 Number 21
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Treatment of Symptomatic Uterine Fibroids

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by The REST Investigators
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To the Editor: In their report on the Randomized Trial of Embolization versus Surgical Treatment for Fibroids (REST), Edwards et al. (Jan. 25 issue)1 carefully discuss the benefits of uterine-artery embolization as compared with hysterectomy but do not address some important potential concerns associated with embolization. The lack of tissue availability for histopathological examination after uterine-artery embolization has been reported to delay diagnosis of a concomitant cancer2 or a malignant mass initially misdiagnosed and treated as a uterine fibroma. Furthermore, concern has been expressed about a decrease in ovarian function after embolization. Women with anastomoses of the uterine and ovarian . . . [Full Text of this Article]



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