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Thirteen years have elapsed since the first edition of this book was published. At that time, heart failure was just being recognized as a cardiovascular condition that had major effects on public health, and that recognition was probably the impetus for writing such a book in the first place. Since then, the remarkable pace of change in our understanding of heart failure has been driven by advances in the biologic sciences, engineering, information technology, and the funding of large trials by industry. The evidence base for choices in the treatment of heart failure is probably greater than in any other
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