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Clinical Practice
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Volume 356:2293-2300 May 31, 2007 Number 22
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Osteopenia
Sundeep Khosla, M.D., and L. Joseph Melton, III, M.D., M.P.H.

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations.

A 55-year-old asymptomatic woman, who is 5 years postmenopausal, is concerned about osteoporosis, since her mother had a hip fracture at the age of 70 years. The patient has no personal history of fractures and has never taken corticosteroids. She does not smoke but does drink one to two glasses of wine a day. Her weight is 105 lb (48 kg), and . . . [Full Text of this Article]

The Clinical Problem

Strategies and Evidence

Additional Testing

            Assessment for Vertebral Fractures

            Markers of Bone Turnover

Watchful Waiting versus Pharmacologic Intervention

            Lifestyle Modifications

            Pharmacologic Therapy

Areas of Uncertainty

Guidelines

Conclusions and Recommendations


Source Information

From the Endocrine Research Unit, Division of Endocrinology and Metabolism, Department of Internal Medicine, and the Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN.

Address reprint requests to Dr. Khosla at the Endocrine Research Unit, Mayo Clinic College of Medicine, 200 First St., SW, 5-194 Joseph, Rochester, MN 55905, or to khosla.sundeep@mayo.edu.




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