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Dr. Surajit Nundy (Department of Medicine): A 25-year-old woman was admitted to this hospital because of a 5-month history of relapsing fevers and a 3-day history of dyspnea. She had been well until early spring, 5 months before admission, when temperatures as high as 39.4°C, neck stiffness, and malaise developed. She was admitted to another hospital 1 month later, and examination of a peripheral-blood smear disclosed parasites that were consistent with babesiosis. Treatment with azithromycin and atovaquone was given for 7 days; her symptoms resolved, and she was discharged on the seventh hospital day.
After discharge, during the summer, she
Pathological Discussion
Differential Diagnosis
Discussion of Management
Antibiotic Therapy for Babesiosis
Fulminant Babesiosis
Persistent or Relapsing Babesiosis
Red-Cell Exchange Transfusion
Rationale for Exchange Transfusion
Risks of Exchange Transfusion
Dr. Jeffrey A. Gelfand's Diagnosis
Pathological Diagnosis
Source Information
From the Blood Transfusion Service (C.P.S.), Infectious Disease Unit (J.A.G.), and the Departments of Radiology (J.-A.O.S.) and Pathology (C.P.S., A.K.), Massachusetts General Hospital; and the Departments of Pathology (C.P.S., A.K.), Medicine (J.A.G.), and Radiology (J.-A.O.S.), Harvard Medical School. (Dr. Kratz is now at the Department of Pathology, College of Physicians and Surgeons, Columbia University, New York.)
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