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Previous Volume 356:2323-2324 May 31, 2007 Number 22 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Nagot et al. (Feb. 22 issue)¹ report that treatment with valacyclovir (1 g per day) to suppress herpes simplex virus (HSV) reduced human immunodeficiency virus type 1 (HIV-1) RNA levels in patients in Burkina Faso. This finding raises important questions regarding the clinical management of HSV infection in poor countries. Of the 68 patients receiving valacyclovir, 3 (4%) had at least one episode of vesicular or genital ulceration during the study period. In another trial,² which showed a reduction of recurrences of HSV type 2 (HSV-2) with valacyclovir (1 g per day) in HIV-infected patients, 3 (6%) . . . [Full Text of this Article]

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