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Previous Volume 356:2343-2346 June 7, 2007 Number 23 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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On May 2, 2007, the Food and Drug Administration (FDA) ordered that all antidepressant medications carry an expanded black-box warning incorporating information about an increased risk of suicidal symptoms in young adults 18 to 24 years of age. Since October 2004, antidepressants have been required to have a black-box warning indicating that they are associated with an increased risk of suicidal thinking, feeling, and behavior in children and adolescents.

The new warning also states that there is no evidence of an increased risk for adults older than 24 years of age and that the risk is actually decreased for adults . . . [Full Text of this Article]

Source Information

Dr. Friedman is a professor of clinical psychiatry and director of the Psychopharmacology Clinic, and Dr. Leon is a professor of biostatistics in psychiatry and a professor of public health, at Weill Cornell Medical College, New York. Dr. Leon is a member of the FDA's Psychopharmacologic Drugs Advisory Committee.

An interview with Dr. Leon can be heard at www.nejm.org.

This article (10.1056/NEJMp078015) was published at www.nejm.org on May 7, 2007.

This article has been cited by other articles:

• Tsapakis*, E. M., Soldani*, F., Tondo, L., Baldessarini, R. J. (2008). Efficacy of antidepressants in juvenile depression: meta-analysis. Br. J. Psychiatry 193: 10-17 [Abstract] [Full Text]  
• James, A. (2008). Pharmacotherapy and child psychiatry: is there a way forward?: INVITED COMMENTARY ON... CHILD PSYCHIATRY AND ITS RELATIONSHIP WITH THE PHARMACEUTICAL INDUSTRY. Adv. Psychiatr. Treat. 14: 10-16 [Abstract] [Full Text]  
• Hickie, I. (2007). Is depression overdiagnosed? No. BMJ 335: 329-329 [Full Text]