For the past decade, women and health care providers have facedconfusing information about the effects of hormone-replacementtherapy, or HRT, on heart disease. Important practical questionshave remained unresolved: Who can safely receive hormone-replacementtherapy? Who is at increased risk from hormone-replacement therapy?Might any women benefit from hormone-replacement therapy forreasons other than relief from menopausal symptoms?
Now, some clarity about hormone-replacement therapy and heartdisease is emerging. New research supports the concept thathormone-replacement therapy has different effects on blood vesselsin younger menopausal women (50 to 59 years old) than in womenlong after menopause, underscoring . . . [Full Text of this Article]
Source Information
From the Molecular Cardiology Research Institute, Tufts–New England Medical Center, Tufts University School of Medicine, Boston.
Related Letters:
Estrogen Therapy and Coronary-Artery Calcification
Hodis H. N., Mack W. J., Brouwer M. A., Dieker H.-J., Verheugt F. W.A., Hofbauer L. C., Khosla S., Schoppet M., Manson J. E., Allison M. A., Rossouw J. E.
Extract |
Full Text |
PDF
N Engl J Med 2007;
357:1252-1254, Sep 20, 2007.
Correspondence
This article has been cited by other articles:
BARLOW, D. H.
(2008). The Medical Management of Menopause: To Treat or Not To Treat?. Ann. N. Y. Acad. Sci.
1127: 134-139
[Abstract][Full Text]
Campbell, D. J.
(2008). Why do men and women differ in their risk of myocardial infarction?. Eur Heart J
29: 835-836
[Full Text]
Jackson, G.
(2008). Gender differences in cardiovascular disease prevention. Menopause Int
14: 13-17
[Abstract][Full Text]
Jacobson, P. D.
(2008). Transforming Clinical Practice Guidelines Into Legislative Mandates: Proceed With Abundant Caution. JAMA
299: 208-210
[Full Text]
Hodis, H. N., Mack, W. J., Brouwer, M. A., Dieker, H.-J., Verheugt, F. W.A., Hofbauer, L. C., Khosla, S., Schoppet, M., Manson, J. E., Allison, M. A., Rossouw, J. E.
(2007). Estrogen Therapy and Coronary-Artery Calcification. NEJM
357: 1252-1254
[Full Text]
Roberts, H.
(2007). Hormone replacement therapy comes full circle. BMJ
335: 219-220
[Full Text]
(2007). Estrogen Therapy Mitigates Risk for Coronary Artery Disease in Younger Menopausal Women. JWatch Women's Health
2007: 2-2
[Full Text]
(2007). More from the Women's Health Initiative: Benefits for Estrogen?. JWatch General
2007: 1-1
[Full Text]