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A 49-year-old woman was seen in the outpatient surgical clinic of this hospital because of a diagnosis of melanoma.
The patient had noted a flat, pigmented lesion on her left upper arm approximately 1 year earlier. Three months later, it began to itch and became slightly raised. Approximately 3 months before the current evaluation, the lesion began to bleed when she scratched it. She saw a dermatologist at another facility, who performed a punch biopsy. Pathological examination was reported to show an atypical Spitz tumor; reexcision was recommended. The lesion was reexcised; pathological examination disclosed a superficial, spreading malignant melanoma,
Pathological Discussion
Pathological Prognostic Factors in Melanoma
Evaluation of Sentinel Lymph Node
Discussion of Management
Surgical Management of Melanoma
Excision Margins
Sentinel Lymph-Node Biopsy
The Role of Sentinel-Node Biopsy in Thin Melanomas
Complete Lymphadenectomy after Detection of a Positive Sentinel Node
Medical Management of Stage IIIa Melanoma
Interferon Therapy for Melanoma
Pathological Diagnosis
Source Information
From the Sydney Melanoma Unit, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, Australia (J.F.T.); the Department of Medical Oncology, Dana–Farber Cancer Institute, and the Department of Medicine, Brigham and Women's Hospital — both in Boston (F.S.H.); the Department of Pathology, Massachusetts General Hospital, Boston (A.Z.); and the Departments of Medicine (F.S.H.) and Pathology (A.Z.), Harvard Medical School, Boston.
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