This Journal feature begins with a case vignette highlightinga common clinical problem. Evidence supporting various strategiesis then presented, followed by a review of formal guidelines,when they exist. The article ends with the author's clinicalrecommendations.
A 68-year-old woman is incidentally found to have a left adrenalmass, 2.8 cm in diameter, on abdominal computed tomography thatwas ordered to evaluate right lower abdominal discomfort (whichhas since resolved). Her medical history is notable only forhypertension that has been well controlled with hydrochlorothiazide,at a dose of 25 mg daily. She reports no sweating, palpitations,headache, weight . . . [Full Text of this Article]
The Clinical Problem
Strategies and Evidence
Hormonal Evaluation
Subclinical Cushing's Syndrome
Clinically Silent Pheochromocytoma
Primary Aldosteronism
Other Hormonally Active Processes
Assessment of Malignant Potential
Size of Adrenal Mass
Imaging Phenotype
Metastatic Disease
Fine-Needle Aspiration Biopsy
Bilateral Adrenal Masses
Areas of Uncertainty
Guidelines
Conclusions and Recommendations
Source Information
From the Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine, Mayo Clinic, Rochester, MN.
Address reprint requests to Dr. Young at the Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, or at young.william@mayo.edu.
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