FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 356:622-624 February 8, 2007 Number 6 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by Legro, R. S.

Of the estimated 6.7 million women with fertility problems in the United States, 35% have received drugs to induce ovulation.¹ The most common cause of anovulation among infertile women is the polycystic ovary syndrome, a condition typically characterized by irregular menses, androgen excess, and polycystic-appearing ovaries. The condition is associated with insulin resistance and obesity.

Although a number of drugs have been used to induce ovulation in women with the polycystic ovary syndrome, clomiphene citrate is a simple, tried-and-true treatment. Clomiphene is an orally active, antiestrogenic substance that promotes the release of follicle-stimulating hormone from the pituitary gland, thus stimulating . . . [Full Text of this Article]

Source Information

From the Department of Obstetrics and Gynecology, University of Rochester School of Medicine and Dentistry, Rochester, NY.

This article has been cited by other articles:

• Palomba, S., Orio, F. Jr., Falbo, A., Russo, T., Tolino, A., Zullo, F. (2007). Clomiphene Citrate Versus Metformin as First-Line Approach for the Treatment of Anovulation in Infertile Patients with Polycystic Ovary Syndrome. J. Clin. Endocrinol. Metab. 92: 3498-3503 [Abstract] [Full Text]  
• (2007). Treating Infertility Caused by Polycystic Ovary Syndrome. JWatch General 2007: 1-1 [Full Text]