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Volume 356:632-634 February 8, 2007 Number 6
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Colonoscopy Screening for Detection of Advanced Neoplasia

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To the Editor: In the cross-sectional study of the detection of advanced neoplasia during colorectal-cancer screening, Regula et al. (Nov. 2 issue)1 observed that Polish men were more than twice as likely as Polish women to have advanced neoplasia. Although they controlled for age and family history, the authors did not examine lifestyle factors known to be associated with colorectal neoplasia.

Clinical studies have consistently shown that current and former smokers have significantly higher rates of colorectal neoplasia than nonsmokers. Results from screening populations have shown that smoking may be at least as potent a risk factor as family history . . . [Full Text of this Article]




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