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Volume 356:662 February 15, 2007 Number 7
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Pulsed Corticosteroid Therapy for Primary Treatment of Kawasaki Disease

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by Burns, J. C.

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by Newburger, J. W.
Children with Kawasaki disease are at risk for the development of coronary-artery aneurysms. Standard therapy for this disorder includes intravenous immune globulin and aspirin. This study shows that, as compared with placebo, the addition of a single pulsed dose of intravenous methylprednisolone has no further beneficial effect over that of standard therapy and therefore cannot be recommended for routine treatment.



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