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Previous Volume 356:830-840 February 22, 2007 Number 8 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The link between myocardial ischemia and obstructive atherosclerosis of the epicardial coronary arteries is well established, and coronary angiography has demonstrated a relationship between the severity and extent of coronary artery disease (CAD) and survival. In the past two decades, however, a number of studies have reported that abnormalities in the function and structure of the coronary microcirculation occur in many clinical conditions. In some instances these abnormalities represent epiphenomena, whereas in others they represent important markers of risk or may even contribute to the pathogenesis of myocardial ischemia, thus becoming therapeutic targets.¹

Functional Anatomy of the Coronary Arterial System

The coronary arterial system is composed of . . . [Full Text of this Article]

Assessment of Coronary Microcirculation

Classification of Coronary Microvascular Dysfunction

Microvascular Dysfunction without CAD or Myocardial Diseases

Cigarette Smoking

Hyperlipidemia

Diabetes

Microvascular Angina

Microvascular Dysfunction with Myocardial Diseases

Primary (Genetic) Cardiomyopathies

            Hypertrophic Cardiomyopathy

            Dilated Cardiomyopathy

Secondary Cardiomyopathies

            Arterial Hypertension

            Aortic Stenosis

            Infiltrative Heart Disease

Microvascular Dysfunction with Obstructive CAD

Stable CAD

Acute Coronary Syndromes without ST-Segment Elevation

Acute Myocardial Infarction with ST-Segment Elevation

Iatrogenic Coronary Microvascular Dysfunction

Conclusions

Source Information

From the Medical Research Council Clinical Sciences Centre and National Heart and Lung Institute, Imperial College, London (P.G.C.); and the Institute of Cardiology, Catholic University, Rome (F.C.).

Address reprint requests to Dr. Camici at the Medical Research Council Clinical Sciences Centre, Hammersmith Hospital, Du Cane Rd., London W12 0NN, United Kingdom, or at paolo.camici@csc.mrc.ac.uk.

Related Letters:

Coronary Microvascular Dysfunction
Duran J. R. III, Taffet G., Camici P. G., Crea F.
Extract | Full Text | PDF  
N Engl J Med 2007; 356:2324-2325, May 31, 2007. Correspondence

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