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Previous Volume 356:876-877 February 22, 2007 Number 8 Next

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(Issues in Biomedical Ethics.) By Lainie Friedman Ross. 285 pp. New York, Oxford University Press, 2006. $74. ISBN 978-0-19-927328-7.

In the past decade, medical research with children has been on the rise, a result of federal legislative and regulatory incentives to include children in pharmaceutical research. Because the vast majority of prescription drugs have been tested only in adults, little is known about the safety and effectiveness of these drugs for use in children. In her examination of the regulatory landscape governing pediatric research and through case studies of several research arenas, Lainie Friedman Ross shows that the push to conduct clinical trials with children raises several ethical and policy issues that have yet to be resolved.

The federal . . . [Full Text of this Article]

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