This Journal feature begins with a case vignette that includesa therapeutic recommendation. A discussion of the clinical problemand the mechanism of benefit of this form of therapy follows.Major clinical studies, the clinical use of this therapy, andpotential adverse effects are reviewed. Relevant formal guidelines,if they exist, are presented. The article ends with the author'sclinical recommendations.
A 73-year-old man with stable coronary artery disease, hypertension,and chronic renal insufficiency presents with recurrent atrialfibrillation at 80 to 90 beats per minute. His symptoms includeshortness of breath and fatigue. He has had atrial fibrillationtwice . . . [Full Text of this Article]
The Clinical Problem
Pathophysiology and Effect of Therapy
Clinical Evidence
Clinical Use
Adverse Effects
Areas of Uncertainty
Guidelines
Recommendations
Source Information
From the Division of Cardiology, Beth Israel Deaconess Medical Center, Boston.
Address reprint requests to Dr. Zimetbaum at Beth Israel Deaconess Medical Center, 185 Pilgrim Rd., Boston, MA 02215, or at pzimetba@bidmc.harvard.edu.
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Amiodarone for Atrial Fibrillation
Rehman H. u., Kurnik D., Loebstein R., Olchovsky D., Coceani M., Skolnik N., Armon C., Zimetbaum P.
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N Engl J Med 2007;
356:2424-2426, Jun 7, 2007.
Correspondence
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