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Volume 357:90-91 July 5, 2007 Number 1
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Viral Hepatitis in HIV Infection

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by Koziel, M. J.
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To the Editor: Koziel and Peters (April 5 issue)1 suggest a list of tests for viral hepatitis in patients with human immunodeficiency virus (HIV) infection. There was, however, no mention of hepatitis delta virus (HDV) infection in association with hepatitis B virus (HBV). Worldwide, 15 million people are infected with HDV,2 and thus it remains an important cause of liver-related illness and death. HDV suppresses HBV replication, so most patients with HDV infection have low levels of HBV DNA2; therefore, clinicians may underestimate disease severity in the absence of liver histologic findings. Furthermore, only interferon-based therapy is currently effective . . . [Full Text of this Article]



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