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Volume 357:91-93 July 5, 2007 Number 1
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Intermittent Claudication

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 by White, C.
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To the Editor: In his review of intermittent claudication, White (March 22 issue)1 emphasizes that patients with this condition are at high risk for cardiovascular events, but he does not emphasize the role of statins in this population. There is good justification for the systematic prescription of statins for patients with peripheral arterial disease. The Heart Protection Study showed that in patients with peripheral arterial disease, aggressive lowering of low-density lipoprotein cholesterol was associated with a marked reduction in cardiovascular events,2 whether or not there was evidence of coronary disease at baseline; there was no apparent threshold cholesterol value below . . . [Full Text of this Article]




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