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Correspondence
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Volume 357:93-94 July 5, 2007 Number 1
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Intravenous Iron

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To the Editor: Before iron was used as an adjunct to erythropoietic stimulatory therapy in patients undergoing hemodialysis, parenteral iron was considered to be dangerous. High-molecular-weight iron dextran (Imferon [Fisons], which is no longer manufactured) was the only product available and was associated with anaphylaxis. Nonetheless, marked improvements in hemoglobin responsiveness1 resulted in the extensive use of high-molecular-weight iron dextran in nephrology. In the mid-1990s, two events changed the prescribing practices of nephrologists. First, high-molecular-weight iron dextran was removed from the market, and subsequently, low-molecular-weight iron dextran (InFed [Watson]) was released. Low-molecular-weight iron dextran was the standard of care for . . . [Full Text of this Article]


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