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This is a comprehensive, well-written, beautifully illustrated book about the disruption of atherosclerotic plaque. Plaque disruption is responsible for more than 75% of acute cardiac events, including myocardial infarction and sudden death. Heart disease has been the leading cause of death in the United States for the past 80 years, and a great majority of these deaths are caused by atherosclerotic coronary artery disease. Epidemiologists tell us that age-standardized mortality rates for myocardial infarction have declined over the past 10 to 15 years. However, the absolute number of deaths from myocardial infarction has actually increased, and now the mortality rate
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