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Volume 357:1052-1053 September 6, 2007 Number 10
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Follow-up of Patients with Early Breast Cancer

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by Hayes, D. F.
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To the Editor: In the review of early breast-cancer management by Hayes (June 14 issue),1 the effects of selective estrogen-receptor modulators on the uterus (shown in Table 5 of the article) might have been clearer if raloxifene, which does not adversely affect endometrial tissues2,3 as tamoxifen does, had been listed separately, as it was in Table 4 of the article.


Hideta Sakemi, M.D.
Rakuwakai Otowa Hospital
Kyoto 607-8062, Japan
rakuwadr073@rakuwadr.com

  1. Hayes DF. Follow-up of patients with early breast cancer. N Engl J Med 2007;356:2505-2513. [Free Full Text]
  2. Jolly EE, Bjarnason NH, Neven P, et al. Prevention of osteoporosis and uterine effects in postmenopausal women taking raloxifene for 5 years. Menopause 2003;10:337-344. [CrossRef][ISI][Medline]
  3. Grady D, Ettinger B, Moscarelli E, et al. Safety and adverse effects associated with raloxifene: multiple outcomes of raloxifene evaluation. Obstet Gynecol 2004;104:837-844. [Free Full Text]
 
To the Editor: The Clinical Practice article by Hayes highlights the problems that face breast-cancer survivors. These patients remain at increased risk for not only recurrence of breast cancer but . . . [Full Text of this Article]



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