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Correspondence
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Volume 357:1162-1163 September 13, 2007 Number 11
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Disappearance of Antibodies to SARS-Associated Coronavirus after Recovery

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To the Editor: Previous studies have demonstrated that IgG and neutralizing antibodies against coronavirus associated with the severe acute respiratory syndrome (SARS) may persist, in spite of a decline in titer, for 2 years in patients who have recovered from SARS.1,2 For 3 years, we followed patients who had recovered from infection with SARS-associated coronavirus, to measure the longevity of specific antibodies.

Fifty-six patients who were positive for serum IgG and neutralizing antibodies against SARS-associated coronavirus at the time of recovery from acute SARS infection were included in this study.1 The titers of IgG and neutralizing antibodies were significantly correlated . . . [Full Text of this Article]




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