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Previous Volume 357:1368-1371 October 4, 2007 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The 2007 Lasker Award for Clinical Medical Research, granted in mid-September to Albert Starr and Alain Carpentier, recognizes their extraordinary contributions to the development of the prosthetic heart valve, which represents a milestone in the journey toward the fabrication of synthetic living tissues and organ systems. The prosthetic heart valve was built on a foundation laid down during the first half of the 20th century with the introduction of cardiac catheterization by André Cournand and Dickinson Richards, the development of innovative surgical techniques by Alfred Blalock, the invention of the heart–lung machine by John Gibbon, and the discovery of heparin . . . [Full Text of this Article]

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Dr. Chaikof is chief of the Division of Vascular Surgery, Department of Surgery, Emory University, and a professor in the Department of Biomedical Engineering and School of Chemical and Biomolecular Engineering, Georgia Institute of Technology — both in Atlanta.

An interview with Dr. Albert Starr, coinventor of the first successful artificial heart valve, can be heard at www.nejm.org.

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