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Correspondence
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Volume 357:1451-1453 October 4, 2007 Number 14
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Tissue-Engineered Blood Vessel for Adult Arterial Revascularization

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To the Editor: A material that will approach the efficacy of native vein has been widely sought.1 Using autologous cells and a technique termed sheet-based tissue engineering, we were able to produce autologous tissue-engineered blood vessels with physiologic mechanical properties.2 No synthetic or exogenous materials were used; instead, the vessels were created with the use of autologous fibroblasts and endothelial cells harvested from a small biopsy specimen of skin and superficial vein. Here we report on the preliminary use of these tissue-engineered blood vessels in an adult arterial model.

Ten patients receiving hemodialysis whose arteriovenous shunts were failing were enrolled . . . [Full Text of this Article]


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