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A 41-year-old man was admitted to this hospital because of abdominal pain, nausea, and an elevated serum creatinine level. He had been in good health until 6 days before admission, when chills and malaise developed. At that time, his body felt warm to the touch, but the temperature was not measured. He took ibuprofen (at a dose of 400 mg) orally every 6 hours for three or four doses, with some improvement in his symptoms. Weakness and nausea developed, and he took one dose of an over-the-counter medication that included acetaminophen, dextromethorphan, and pseudoephedrine, with improvement in his symptoms.
Two
Differential Diagnosis
Acute Kidney Injury
Tubulointerstitial Causes
Glomerular Causes
Urinalysis
NSAIDs
Clinical Diagnosis
Dr. Hamid Rabb's Diagnoses
Pathological Discussion
Anatomical Diagnosis
Source Information
From the Nephrology Division, Johns Hopkins Hospital, and the Department of Medicine, Johns Hopkins University School of Medicine, Baltimore (H.R.); and the Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston (R.B.C.).
Related Letters:
Case 31-2007: A Man with Abdominal Pain and Elevated Creatinine
Haas C. S., Devarajan P., Parikh C., Barasch J., Kleeman F. J., Rabb H., Colvin R. B.
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N Engl J Med 2008;
358:312-313, Jan 17, 2008.
Correspondence
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