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Previous Volume 357:1545-1547 October 11, 2007 Number 15 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In the first half of the past century, it was thought that asthma was precipitated or prolonged by infection and that infection with several bacteria, including Streptococcus pneumoniae and Haemophilus influenzae, had a role in asthma.¹ Some investigators had suggested that bacterial allergy or chronic focal infection could be a cause of asthma.² More recently, population-based studies relating infections with Chlamydia pneumoniae and Mycoplasma pneumoniae to asthma severity encouraged a resurgent debate, but clinical trials involving various antibiotics failed to demonstrate sustained clinical benefit.¹

To understand this debate we need to consider asthma and wheeze in children. The greatest incidence . . . [Full Text of this Article]

Source Information

From the University Children's Hospital, Munich, Germany.

Related Letters:

Asthma and Neonatal Airway Colonization
Michelow I. C., Fracchia M. S., Kinane T. B., Stallings A. P., Commins S. P., Platts-Mills T. A.E., Hughes-Davies T., Nanan R. K.H., Peek M. J., Bisgaard H., Bønnelykke K., Pipper C., von Mutius E.
Extract | Full Text | PDF  
N Engl J Med 2008; 358:423-425, Jan 24, 2008. Correspondence

This article has been cited by other articles:

• Michelow, I. C., Fracchia, M. S., Kinane, T. B., Stallings, A. P., Commins, S. P., Platts-Mills, T. A.E., Hughes-Davies, T., Nanan, R. K.H., Peek, M. J., Bisgaard, H., Bonnelykke, K., Pipper, C., von Mutius, E. (2008). Asthma and Neonatal Airway Colonization. NEJM 358: 423-425 [Full Text]  
• (2007). Does Neonatal Airway Colonization Cause Asthma?. JWatch Pediatrics 2007: 2-2 [Full Text]