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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.
A 45-year-old white woman presents with a 1-year history of scalp-hair loss. She was hospitalized with appendicitis 14 months ago. She has been a vegetarian for 20 years. She takes no medications. Her father was bald. On physical examination, she has diffuse, nonscarring hair thinning with a widened part over the central portion of the scalp. How should this problem be evaluated
The Clinical Problem
Hair Biology
Causes of Hair Loss
Strategies and Evidence
Evaluation
Laboratory Testing
Management
Minoxidil Solution
Antiandrogen Therapies
Hair Transplantation
Treatment of Other Causes of Hair Loss
Areas of Uncertainty
Guidelines
Conclusions and Recommendations
Source Information
From the Department of Dermatology and Skin Science, University of British Columbia, and Vancouver Coastal Health Research Institute — both in Vancouver, Canada; and the Department of Dermatology, New York University, New York.
Address reprint requests to Dr. Shapiro at the Department of Dermatology and Skin Science, University of British Columbia, 835 W. 10th Ave., Vancouver, BC V5Z 4E8, Canada.
Related Letters:
Hair Loss in Women
Schlegel A., Shapiro J.
Extract |
Full Text |
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N Engl J Med 2008;
358:533-534, Jan 31, 2008.
Correspondence
This article has been cited by other articles:
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