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Previous Volume 357:1640-1648 October 18, 2007 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Presentation of Case

Dr. David A. Barbie (Medical Oncology): A 62-year-old woman came to this hospital for management of breast cancer.

Six years earlier, a routine mammogram had revealed calcifications in the left breast. Specimens from a stereotactically guided core biopsy showed atypical cells, and an excisional biopsy with needle localization showed a grade 1 invasive ductal carcinoma of the left breast, 0.7 cm in maximal diameter, associated with intermediate-grade ductal carcinoma in situ. The tumor extended within 0.2 cm of the margin; there was no lymphovascular invasion. The tumor cells expressed estrogen and progesterone receptors and did not overexpress human epidermal growth . . . [Full Text of this Article]

Differential Diagnosis

Pathological Discussion

Discussion of Management

Local Treatment of Contralateral Breast Cancer

Adjuvant Systemic Therapy for Breast Cancer

            Assessing the Risks of Recurrence and Death from Breast Cancer

            Adjuvant Endocrine Therapy

            Adjuvant Chemotherapy

            Trastuzumab in HER2-Positive Breast Cancer

Care of This Patient

Anatomical Diagnosis

Source Information

From the Departments of Medical Oncology (E.P.W.) and Radiation Oncology (J.R.H.), Dana–Farber Cancer Institute and Brigham and Women's Hospital; the Departments of Medicine (E.P.W.), Radiation Oncology (J.R.H.), Surgery (B.L.S.), Radiology (H.A.D.), and Pathology (E.F.B.), Harvard Medical School; and the Departments of Surgical Oncology (B.L.S.), Radiology (H.A.D.), and Pathology (E.F.B.), Massachusetts General Hospital — all in Boston.

Related Letters:

Case 32-2007: Bilateral Breast Cancer
Morrison P. J., Winer E. P., Harris J., Smith B. L.
Extract | Full Text | PDF  
N Engl J Med 2008; 358:970, Feb 28, 2008. Correspondence

This article has been cited by other articles:

• Morrison, P. J., Winer, E. P., Harris, J., Smith, B. L. (2008). Case 32-2007: Bilateral Breast Cancer. NEJM 358: 970-970 [Full Text]