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Previous Volume 357:1775-1777 October 25, 2007 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In his Perspective article (Aug. 30 issue),¹ Dr. Rosen discusses the recent Food and Drug Administration (FDA) advisory committee meeting on rosiglitazone. He also calls for approval of antidiabetic drugs based on long-term clinical outcomes, not on the surrogate of glycated hemoglobin, a measure of glycemic control. Although he does not describe a specific study, we assume he is suggesting that approval should require evidence that cardiovascular events, a major long-term complication of diabetes mellitus, are reduced. This change could have major implications for the availability of treatments for type 2 diabetes.

All drugs currently approved for . . . [Full Text of this Article]

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