To the Editor: In their letter to the editor, Budach et al.(Aug. 2 issue)1 report on two patients with squamous-cell carcinomaof the head and neck who had severe radiation dermatitis whilereceiving a combination of radiotherapy and cetuximab, a regimenfound to be superior to radiotherapy alone in our proof-of-conceptphase 3 trial.2 Severe radiation dermatitis can occur afterirradiation alone, but grade 4 dermatitis is rarely observed.In reviewing the case histories of the patients, Budach et al.note that Patient 1 had previously received etoposide-basedtherapy and Patient 2 had previously received a full courseof . . . [Full Text of this Article]
Jatoi, A., Nguyen, P. L.
(2008). Do Patients Die from Rashes from Epidermal Growth Factor Receptor Inhibitors? A Systematic Review to Help Counsel Patients About Holding Therapy. The Oncologist
13: 1201-1204
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