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Previous Volume 357:1939-1945 November 8, 2007 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the author's clinical recommendations.

An 82-year-old widowed woman with a history of recurrent unipolar major depression is referred to the electroconvulsive therapy (ECT) service of an academic medical center. During her illness, she has had four episodes of major depression consisting of periods . . . [Full Text of this Article]

The Clinical Problem

Pathophysiology and Effect of Therapy

Clinical Evidence

Clinical Use

Adverse Effects

Areas of Uncertainty

Guidelines

Recommendations

Source Information

From the Division of Brain Stimulation and Therapeutic Modulation, New York State Psychiatric Institute; and the Department of Psychiatry, Columbia University College of Physicians and Surgeons — both in New York.

Address reprint requests to Dr. Lisanby at the Division of Brain Stimulation and Therapeutic Modulation, New York State Psychiatric Institute, Department of Psychiatry, Columbia University College of Physicians and Surgeons, 1051 Riverside Dr., Unit 21, New York, NY 10032, or at depression@columbia.edu.

Related Letters:

Electroconvulsive Therapy for Depression
Dettling M., Anghelescu I., Bajbouj M., Guevara-Cuellar C. A., Pineda-Cañar C. A., Torri A., Seiner S., Lisanby S. H.
Extract | Full Text | PDF  
N Engl J Med 2008; 358:645-646, Feb 7, 2008. Correspondence

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• Dettling, M., Anghelescu, I., Bajbouj, M., Guevara-Cuellar, C. A., Pineda-Canar, C. A., Torri, A., Seiner, S., Lisanby, S. H. (2008). Electroconvulsive Therapy for Depression. NEJM 358: 645-646 [Full Text]