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Previous Volume 357:1974-1976 November 8, 2007 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Hepatocellular carcinoma is an important disease worldwide, with an increasing incidence in the United States. The large majority of cases occur in patients with chronic infection with hepatitis B virus (HBV) or hepatitis C virus (HCV). The relative risk of hepatocellular carcinoma in patients with chronic HBV or HCV infection is about 25 to 30 times that of those without infection. The inflammatory immune response of the host to viral antigens induces hepatocyte damage, which is followed by the regeneration of hepatocytes and the development of fibrosis and cirrhosis — important features in the pathogenesis of hepatocellular carcinoma.

Men have . . . [Full Text of this Article]

Source Information

From the Warren Alpert Medical School of Brown University, Providence, RI.

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