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Editorial
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Volume 357:176-178 July 12, 2007 Number 2
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Shortened Therapy for Hepatitis C Virus Genotype 2 or 3 — Is Less More?
T. Jake Liang, M.D.

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-Related Article
 by Shiffman, M. L.
-PubMed Citation
Infection with hepatitis C virus (HCV) is a major worldwide cause of chronic liver disease, cirrhosis, and liver cancer, which together represent a chief global public health burden. Therapy has improved substantially since the introduction of interferon-alfa monotherapy in the late 1980s, when the response rate was less than 10%; now, combination therapy with peginterferon and ribavirin has a success rate of about 50%.1,2 Much like the diverse outcomes of HCV infection, the response to treatment varies. Important factors associated with treatment response include the race, age, sex, weight, and biochemical and histologic characteristics of patients. However, viral genotype and, . . . [Full Text of this Article]


Source Information

From the Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.


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