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This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the authors' clinical recommendations.
A 4-month-old baby girl whose parents and 6-year-old brother have severe-to-profound sensorineural hearing loss is referred for consideration for cochlear implantation. Each of the baby's parents had previously received a cochlear implant in adulthood, and her older brother had
The Clinical Problem
Pathophysiology and Effect of Therapy
Clinical Evidence
Clinical Use
Adverse Effects
Areas of Uncertainty
Guidelines
Recommendations
Source Information
From the Department of Otolaryngology, Hospital for Sick Children; and the University of Toronto — both in Toronto.
Address reprint requests to Dr. Gordon at the Department of Otolaryngology, Hospital for Sick Children, 555 University Ave., Rm. 6D08, Toronto, ON M5G 1X8, Canada, or at karen.gordon@utoronto.ca.
Related Letters:
Cochlear Implants
Malekpour M., Napoli D. J., Papsin B. C., Gordon K. A.
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N Engl J Med 2008;
358:1522-1524, Apr 3, 2008.
Correspondence
This article has been cited by other articles:
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