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Correspondence
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Volume 357:2636-2637 December 20, 2007 Number 25
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Gynecomastia

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by Braunstein, G. D.
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To the Editor: In his review of gynecomastia, Dr. Braunstein (Sept. 20 issue)1 includes numerous medications that may be associated with gynecomastia but does not mention a potential link of statins to gynecomastia. The only medication used by the patient described in the clinical vignette was a statin, and case reports have suggested that statins might induce gynecomastia.2,3 In one case report, the gynecomastia was reversed after a change in statin medication.2 A possible mechanism for this relationship is a reduction in adrenal or gonadal steroid production through the effects of statins on the cholesterol pathway.2


Isabela Romao, M.D.
Evan . . . [Full Text of this Article]



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