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Previous Volume 357:2653-2655 December 27, 2007 Number 26 Next

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In April 1984, when the human immunodeficiency virus (HIV) and AIDS were just beginning to be understood, a senior official in the Department of Health and Human Services stated at a press conference that there would be a marketable vaccine within "a minimum of two years, probably more like three years."¹ This prediction has haunted the search for an AIDS vaccine, whose most recent setback was the announcement that a promising vaccine candidate, Merck's V520, was not effective and may actually have increased some subjects' risk of acquiring HIV. Unfortunately, about a quarter-century after the discovery of HIV, there is . . . [Full Text of this Article]

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Dr. Steinbrook (rsteinbrook@attglobal.net) is a national correspondent for the Journal.

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