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Correspondence
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Volume 357:2734-2736 December 27, 2007 Number 26
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Multiple Autoimmune Diseases after Autologous Stem-Cell Transplantation

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To the Editor: Hematopoietic stem-cell transplantation can be an effective treatment in patients with refractory systemic sclerosis.1 We report on a 19-year-old woman with systemic sclerosis who underwent CD34+-selected autologous hematopoietic stem-cell transplantation in March 2001. Before the transplantation, the physical and laboratory findings showed no evidence of any other autoimmune diseases. After written consent was obtained from the patient, CD34+ hematopoietic stem cells were transplanted according to a method used for systemic sclerosis.1 The dermal sclerosis improved immediately after transplantation, but thrombocytopenia and Graves' disease developed.

In June 2005, the patient was admitted to the hospital because of fever . . . [Full Text of this Article]


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