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Volume 357:301-302 July 19, 2007 Number 3
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Transfusion in Pediatric Intensive Care Units

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 by Lacroix, J.
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To the Editor: Lacroix et al. (April 19 issue)1 report that a restrictive transfusion strategy (a hemoglobin threshold of 7 g per deciliter) is as safe as a liberal strategy (a hemoglobin threshold of 9.5 g per deciliter) in pediatric patients in the intensive care unit whose condition is clinically stable. With regard to long-term safety, however, the risk of disease transmission is unquantifiable, and for this reason, the reduction in the number of transfusions is an important end point. We note that 14% of patients in the restrictive-strategy group and 37% in the liberal-strategy group had more than one . . . [Full Text of this Article]




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