A recent study reported that among people who carried a singlecopy of the high-risk allele for the FTO gene, which is associatedwith fat mass and obesity, the risk of obesity increased by30%. The risk of obesity increased by 67% among people who carriedtwo alleles, and on average they gained 3.0 kg (6.6 lb) or more.1Given that approximately one sixth of the population of Europeandescent is homozygous for this allele, this link between theFTO gene and obesity appears to be one of the strongest genotype–phenotypeassociations detected by modern genome-screening techniques.
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