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STATISTICS AND MEDICINE Previous Volume 357:436-439 August 2, 2007 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Editorial by Drazen, J. M. Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by Samani, N. J. PubMed Citation

The past 3 months have seen the publication of a series of studies examining the inherited genetic underpinnings of common diseases such as prostate cancer, breast cancer, diabetes, and in this issue of the Journal, coronary artery disease (reported by Samani et al., pages 443–453). These genomewide association studies have been able to examine interpatient differences in inherited genetic variability at an unprecedented level of resolution, thanks to the development of microarrays, or chips, capable of assessing more than 500,000 single-nucleotide polymorphisms (SNPs) in a single sample. This "SNP-chip" technology capitalizes on a catalogue of common human genetic variations that . . . [Full Text of this Article]

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Dr. Hunter is a professor of epidemiology at the Harvard School of Public Health, Boston, a statistical consultant to the Journal, and codirector of the National Cancer Institute's Cancer Genetic Markers of Susceptibility project. Dr. Kraft is an assistant professor of epidemiology and biostatistics at the Harvard School of Public Health, Boston.

This article (10.1056/NEJMp078120) was published at www.nejm.org on July 18, 2007.

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