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Correspondence
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Volume 357:514-515 August 2, 2007 Number 5
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Severe Cutaneous Reaction during Radiation Therapy with Concurrent Cetuximab

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To the Editor: Cetuximab given concurrently with radiotherapy has recently been reported to result in a survival benefit for patients with locally advanced squamous-cell carcinoma of the head and neck, without increasing the toxic effects of radiotherapy.1 We report two cases of severe radiation dermatitis during the course of radiotherapy for squamous-cell carcinoma of the head and neck with concomitant use of cetuximab; these two cases of dermatitis occurred among five patients treated according to this protocol at our institution.

Patient 1 was a 57-year-old woman with grade 2 squamous-cell carcinoma of the head and neck (cT3cN0cM0), and Patient 2 . . . [Full Text of this Article]


Related Letters:

More on Severe Cutaneous Reaction with Radiotherapy and Cetuximab
Bonner J. A., Ang K., Budach W., Bölke E., Homey B.
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N Engl J Med 2007; 357:1872-1873, Nov 1, 2007. Correspondence

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