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Previous Volume 357:572-579 August 9, 2007 Number 6 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations.

A 62-year-old man has sudden weakness of the left arm and leg and slurred speech. Except for untreated hypertension, his medical history is unremarkable. He is a current smoker with a smoking history of 45 pack-years. On arrival at the emergency department 1 hour 15 minutes after the onset of symptoms, he reports no headache or vomiting. His blood pressure is 180/100 . . . [Full Text of this Article]

The Clinical Problem

Strategies and Evidence

Initial Assessment

Imaging

Intravenous Thrombolysis

Other Treatments

            Aspirin

            Anticoagulant Therapy

Prevention and Management of Complications

Strategies to Reduce Risk of Recurrent Stroke or Other Cardiovascular Events

Areas of Uncertainty

Other Treatments

Neuroprotection

Guidelines from Professional Societies

Conclusions and Recommendations

Source Information

From the Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, the Netherlands.

Address reprint requests to Dr. van der Worp at the Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands, or at h.b.vanderworp@umcutrecht.nl.

Related Letters:

Acute Ischemic Stroke
Chiti A., Giorli E., Orlandi G., Mumoli N., Cei M., van der Worp H. B., van Gijn J.
Extract | Full Text | PDF  
N Engl J Med 2007; 357:2203-2204, Nov 22, 2007. Correspondence

This article has been cited by other articles:

• Chiti, A., Giorli, E., Orlandi, G., Mumoli, N., Cei, M., van der Worp, H. B., van Gijn, J. (2007). Acute ischemic stroke.. NEJM 357: 2203-2203 [Full Text]