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A 20-year-old pregnant woman was admitted to this hospital at 26 weeks of gestation because of dizziness, confusion, and difficulty walking.
Ten weeks before admission, the patient had a positive result on a home pregnancy test and presented to a neighborhood health center for prenatal screening. Tests for sickle cell trait, syphilis, and human immunodeficiency virus (HIV) and hepatitis B and C virus antibodies were negative. Serologic tests for varicella–zoster virus and rubella IgG were positive. Two weeks later, an endocervical specimen was positive for Chlamydia trachomatis infection and negative for gonorrhea. The patient missed follow-up appointments, and treatment with
Differential Diagnosis
Cerebrospinal Fluid Examination
Electroencephalographic Studies
Disorders of Movement
Acute Viral Encephalitis
Subacute Encephalitides
Paraneoplastic Encephalitis
Postinfectious Encephalitis
Subacute Sclerosing Panencephalitis
Discussion of Management
Dr. Andrew J. Cole's Diagnosis
Pathological Discussion
Anatomical Diagnosis
Source Information
From the Neurology Service (A.J.C., J.W.H., M.P.F.) and the Departments of Radiology (J.W.H.) and Pathology (M.H.A.R., M.P.F.), Massachusetts General Hospital; and the Departments of Neurology (A.J.C., J.W.H.) and Pathology (M.H.A.R., M.P.F.), Harvard Medical School.
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