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Case Records of the Massachusetts General Hospital
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Volume 357:692-701 August 16, 2007 Number 7
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Case 25-2007 — A 60-Year-Old Man with Fever, Odynophagia, Weight Loss, and Rash
Mandakolathur R. Murali, M.D., Bonnie T. Mackool, M.D., Victorine V. Muse, M.D., Artur Zembowicz, M.D., Ph.D., and Judith A. Ferry, M.D.

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Presentation of Case

Dr. Sheila F. Mitsuma (Department of Medicine): A 60-year-old man was admitted to this hospital because of fever, odynophagia, weight loss, and rash.

He had been well until 5 months earlier, when he began to have fatigue and malaise, as well as decreased appetite, and he lost 7.3 kg of weight. Four weeks before admission, a constant ache developed in the upper oropharynx, which was exacerbated by swallowing. It was accompanied by a dry cough and diffuse arthralgias and myalgias. Two weeks before admission, the patient saw his primary care provider, who prescribed amoxicillin. The symptoms persisted, and a pruritic, . . . [Full Text of this Article]

Differential Diagnosis

Infectious Diseases

Neoplasms

Hypersensitivity and Autoimmune Diseases

Systemic Lupus Erythematosus

Dr. Mandakolathur R. Murali's Diagnosis

Pathological Discussion

Anatomical Diagnoses


Source Information

From the Departments of Medicine (M.R.M.), Dermatology (B.T.M.), Radiology (V.V.M.), and Pathology (A.Z., J.A.F.), Massachusetts General Hospital; and the Departments of Medicine (M.R.M.), Dermatology (B.T.M.), Radiology (V.V.M.), and Pathology (A.Z., J.A.F.), Harvard Medical School.




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