Today, 350 years after its first description, the restless legssyndrome (RLS) is strangely controversial. Experts and patientsalike describe RLS both as a miserably impairing disorder andas "the most common disorder you have never heard of." Criticsdo not regard RLS as a disorder at all but, rather, as the fabricationof an omnivorous pharmaceutical industry. RLS is a waking sensorimotordisturbance with features of both neurologic and sleep disorders.Those afflicted describe an intensely uncomfortable, overwhelmingurge to move the legs (often accompanied by dysesthesias), predominantlyin the evening or at night, that is present at rest . . . [Full Text of this Article]
Source Information
From the Division of Sleep Medicine, Brigham and Women's Hospital, and Harvard Medical School — both in Boston.
This article (10.1056/NEJMe078129) was published at www.nejm.org on July 18, 2007.
This article has been cited by other articles:
Vilarino-Guell, C., Farrer, M. J., Lin, S.-C., Woloshin, S., Schwartz, L. M.
(2008). A Genetic Risk Factor for Periodic Limb Movements in Sleep. NEJM
358: 425-428
[Full Text]