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Correspondence
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Volume 357:719-720 August 16, 2007 Number 7
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Wine-Induced Anaphylaxis and Sensitization to Hymenoptera Venom

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To the Editor: Alcoholic drinks have been described as triggering or initiating anaphylactoid reactions.1 Although little is known about the pathogenesis of these reactions,2 wine contains many biologic and chemical components derived from grapevines, yeast, bacteria, and insects (including those of the order Hymenoptera) that might explain the observed symptoms.3,4

We report on five patients who presented with symptoms after drinking grape juice or newly pressed wines (both red and white). Three of the patients had an oral allergy syndrome and facial flushing, one had asthmatic symptoms, and one had anaphylaxis. Skin tests with conventional allergens, including commercial grape extract, . . . [Full Text of this Article]




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