Acute renal failure is defined as a rapid decrease in the glomerularfiltration rate, occurring over a period of minutes to days.Because the rate of production of metabolic waste exceeds therate of renal excretion in this circumstance, serum concentrationsof markers of renal function, such as urea and creatinine, rise.The causes of acute renal failure are classically divided intothree categories: prerenal, postrenal (or obstructive), andintrinsic. Prerenal azotemia is considered a functional responseto renal hypoperfusion, in which renal structure and microstructureare preserved. Postrenal azotemia — obstruction of theurinary tract — is initially accompanied . . . [Full Text of this Article]
Renal Response to Ischemia
Factors Increasing Renal Susceptibility to Ischemia
Low-Perfusion States in Normotensive Renal Failure
Diagnosis of Normotensive Ischemic Acute Renal Failure
Laboratory Findings
Therapy and Response
Conclusions
Source Information
From the Division of Kidney Disease and Hypertension, Department of Medicine, Rhode Island Hospital and the Warren Alpert Medical School of Brown University, Providence, RI.
Address reprint requests to Dr. Abuelo at the Division of Kidney Disease and Hypertension, Rhode Island Hospital, 593 Eddy St., Providence, RI 02903, or at jgabuelo@lifespan.org.
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