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Previous Volume 357:797-805 August 23, 2007 Number 8 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Acute renal failure is defined as a rapid decrease in the glomerular filtration rate, occurring over a period of minutes to days. Because the rate of production of metabolic waste exceeds the rate of renal excretion in this circumstance, serum concentrations of markers of renal function, such as urea and creatinine, rise. The causes of acute renal failure are classically divided into three categories: prerenal, postrenal (or obstructive), and intrinsic. Prerenal azotemia is considered a functional response to renal hypoperfusion, in which renal structure and microstructure are preserved. Postrenal azotemia — obstruction of the urinary tract — is initially accompanied . . . [Full Text of this Article]

Renal Response to Ischemia

Factors Increasing Renal Susceptibility to Ischemia

Low-Perfusion States in Normotensive Renal Failure

Diagnosis of Normotensive Ischemic Acute Renal Failure

Laboratory Findings

Therapy and Response

Conclusions

Source Information

From the Division of Kidney Disease and Hypertension, Department of Medicine, Rhode Island Hospital and the Warren Alpert Medical School of Brown University, Providence, RI.

Address reprint requests to Dr. Abuelo at the Division of Kidney Disease and Hypertension, Rhode Island Hospital, 593 Eddy St., Providence, RI 02903, or at jgabuelo@lifespan.org.

Related Letters:

Normotensive Ischemic Acute Renal Failure
Rosenberger C., Rosen S., Heyman S. N., Bellomo R., Kellum J. A., Bagshaw S. M., Abuelo J. G.
Extract | Full Text | PDF  
N Engl J Med 2007; 357:2204-2206, Nov 22, 2007. Correspondence

This article has been cited by other articles:

• Ricci, Z., Ronco, C. (2008). Kidney diseases beyond nephrology: intensive care. Nephrol Dial Transplant 23: 820-826 [Full Text]  
• Rosenberger, C., Rosen, S., Heyman, S. N., Bellomo, R., Kellum, J. A., Bagshaw, S. M., Abuelo, J. G. (2007). Normotensive Ischemic Acute Renal Failure. NEJM 357: 2204-2206 [Full Text]