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A 46-year-old woman with metastatic sarcoma who had been treated with five cycles of doxorubicin, ifosfamide, and mesna chemotherapy presented with two symmetrical, horizontal white lines on all of her fingernails but not on her toenails. A diagnosis of Muehrcke's lines was made. Muehrcke's lines are the two smooth white bands that run parallel to the lunula across the width of the nail. The lines are nonpalpable and, unlike Beau's lines, do not indent the nail itself. Normal-appearing pink nail-bed tissue is seen between the two white lines, and thumb involvement is rare. Muehrcke's lines are a nonspecific finding that . . . [Full Text of this Article] |